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A dual molecular analogue tuner for dissecting protein function in mammalian cells
Loss-of-function studies are fundamental for dissecting gene function. Yet, methods to rapidly and effectively perturb genes in mammalian cells, and particularly in stem cells, are scarce. Here we present a system for simultaneous conditional regulation of two different proteins in the same mammalia...
Autores principales: | Brosh, Ran, Hrynyk, Iryna, Shen, Jessalyn, Waghray, Avinash, Zheng, Ning, Lemischka, Ihor R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895048/ https://www.ncbi.nlm.nih.gov/pubmed/27230261 http://dx.doi.org/10.1038/ncomms11742 |
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