Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8(+) T Cells

Curing HIV-1 infection will require elimination of persistent cellular reservoirs that harbor latent virus in the face of combination antiretroviral therapy (cART). Proposed immunotherapeutic strategies to cure HIV-1 infection include enhancing lysis of these infected cells by cytotoxic T lymphocyte...

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Detalles Bibliográficos
Autores principales: Smith, Kellie N., Mailliard, Robbie B., Piazza, Paolo A., Fischer, Will, Korber, Bette T., Fecek, Ronald J., Ratner, Deena, Gupta, Phalguni, Mullins, James I., Rinaldo, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895106/
https://www.ncbi.nlm.nih.gov/pubmed/27247230
http://dx.doi.org/10.1128/mBio.00473-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895106/
https://www.ncbi.nlm.nih.gov/pubmed/27247230
http://dx.doi.org/10.1128/mBio.00473-16

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