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Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8(+) T Cells

Curing HIV-1 infection will require elimination of persistent cellular reservoirs that harbor latent virus in the face of combination antiretroviral therapy (cART). Proposed immunotherapeutic strategies to cure HIV-1 infection include enhancing lysis of these infected cells by cytotoxic T lymphocyte...

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Detalles Bibliográficos
Autores principales:	Smith, Kellie N., Mailliard, Robbie B., Piazza, Paolo A., Fischer, Will, Korber, Bette T., Fecek, Ronald J., Ratner, Deena, Gupta, Phalguni, Mullins, James I., Rinaldo, Charles R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895106/ https://www.ncbi.nlm.nih.gov/pubmed/27247230 http://dx.doi.org/10.1128/mBio.00473-16

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