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Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway

Chitin is an important cell wall component of Aspergillus fumigatus conidia, of which hundreds are inhaled on a daily basis. Previous studies have shown that chitin has both anti- and proinflammatory properties; however the exact mechanisms determining the inflammatory signature of chitin are poorly...

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Detalles Bibliográficos
Autores principales: Becker, K. L., Aimanianda, V., Wang, X., Gresnigt, M. S., Ammerdorffer, A., Jacobs, C. W., Gazendam, R. P., Joosten, L. A. B., Netea, M. G., Latgé, J. P., van de Veerdonk, F. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895119/
https://www.ncbi.nlm.nih.gov/pubmed/27247234
http://dx.doi.org/10.1128/mBio.01823-15