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Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway
Chitin is an important cell wall component of Aspergillus fumigatus conidia, of which hundreds are inhaled on a daily basis. Previous studies have shown that chitin has both anti- and proinflammatory properties; however the exact mechanisms determining the inflammatory signature of chitin are poorly...
Autores principales: | Becker, K. L., Aimanianda, V., Wang, X., Gresnigt, M. S., Ammerdorffer, A., Jacobs, C. W., Gazendam, R. P., Joosten, L. A. B., Netea, M. G., Latgé, J. P., van de Veerdonk, F. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895119/ https://www.ncbi.nlm.nih.gov/pubmed/27247234 http://dx.doi.org/10.1128/mBio.01823-15 |
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