Efficient Use of a Crude Drug/Herb Library Reveals Ephedra Herb As a Specific Antagonist for T(H)2-Specific Chemokine Receptors CCR3, CCR4, and CCR8

Chemokine receptors CCR3 and CCR4 are preferentially expressed by T(H)2 cells, mast cells, and/or eosinophils, all of which are involved in the pathogenesis of allergic diseases. Therefore, CCR3 and CCR4 have long been highlighted as potent therapeutic targets for allergic diseases. Japanese traditi...

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Detalles Bibliográficos
Autores principales: Matsuo, Kazuhiko, Koizumi, Keiichi, Fujita, Mitsugu, Morikawa, Toshio, Jo, Michiko, Shibahara, Naotoshi, Saiki, Ikuo, Yoshie, Osamu, Nakayama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895122/
https://www.ncbi.nlm.nih.gov/pubmed/27376063
http://dx.doi.org/10.3389/fcell.2016.00054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895122/
https://www.ncbi.nlm.nih.gov/pubmed/27376063
http://dx.doi.org/10.3389/fcell.2016.00054

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