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Requirements for nucleocapsid-mediated regulation of reverse transcription during the late steps of HIV-1 assembly
HIV-1 is a retrovirus replicating within cells by reverse transcribing its genomic RNA (gRNA) into DNA. Within cells, virus assembly requires the structural Gag proteins with few accessory proteins, notably the viral infectivity factor (Vif) and two copies of gRNA as well as cellular factors to conv...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895152/ https://www.ncbi.nlm.nih.gov/pubmed/27273064 http://dx.doi.org/10.1038/srep27536 |