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The morphogen Decapentaplegic employs a two-tier mechanism to activate target retinal determining genes during ectopic eye formation in Drosophila

Understanding the role of morphogen in activating its target genes, otherwise epigenetically repressed, during change in cell fate specification is a very fascinating yet relatively unexplored domain. Our in vivo loss-of-function genetic analyses reveal that specifically during ectopic eye formation...

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Detalles Bibliográficos
Autores principales: Aggarwal, Poonam, Gera, Jayati, Mandal, Lolitika, Mandal, Sudip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895176/
https://www.ncbi.nlm.nih.gov/pubmed/27270790
http://dx.doi.org/10.1038/srep27270