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Nuclear transport of paxillin depends on focal adhesion dynamics and FAT domains

The nuclear transport of paxillin appears to be crucial for paxillin function but the mechanism of transport remains unclear. Here, we show that the nuclear transport of paxillin is regulated by focal adhesion turnover and the presence of FAT domains. Focal adhesion turnover was controlled using tri...

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Detalles Bibliográficos
Autores principales: Sathe, Aneesh R., Shivashankar, G. V., Sheetz, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895192/
https://www.ncbi.nlm.nih.gov/pubmed/27068537
http://dx.doi.org/10.1242/jcs.172643