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Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers

Hepatocellular carcinoma (HCC) cell lines are useful in vitro models for the study of primary HCCs. Because cell lines acquire additional mutations in culture, it is important to understand to what extent HCC cell lines retain the genetic landscapes of primary HCCs. Most HCC cell lines were establis...

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Detalles Bibliográficos
Autores principales: Qiu, Zhixin, Zou, Keke, Zhuang, Liping, Qin, Jianjie, Li, Hong, Li, Chao, Zhang, Zhengtao, Chen, Xiaotao, Cen, Jin, Meng, Zhiqiang, Zhang, Haibin, Li, Yixue, Hui, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895220/
https://www.ncbi.nlm.nih.gov/pubmed/27273737
http://dx.doi.org/10.1038/srep27411