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A maximum-likelihood approach for building cell-type trees by lifting

BACKGROUND: In cell differentiation, a less specialized cell differentiates into a more specialized one, even though all cells in one organism have (almost) the same genome. Epigenetic factors such as histone modifications are known to play a significant role in cell differentiation. We previously i...

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Detalles Bibliográficos
Autores principales: Nair, Nishanth Ulhas, Hunter, Laura, Shao, Mingfu, Grnarova, Paulina, Lin, Yu, Bucher, Philipp, E. Moret, Bernard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895258/
https://www.ncbi.nlm.nih.gov/pubmed/26819094
http://dx.doi.org/10.1186/s12864-015-2297-3