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A maximum-likelihood approach for building cell-type trees by lifting
BACKGROUND: In cell differentiation, a less specialized cell differentiates into a more specialized one, even though all cells in one organism have (almost) the same genome. Epigenetic factors such as histone modifications are known to play a significant role in cell differentiation. We previously i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895258/ https://www.ncbi.nlm.nih.gov/pubmed/26819094 http://dx.doi.org/10.1186/s12864-015-2297-3 |