Characterizing redescriptions using persistent homology to isolate genetic pathways contributing to pathogenesis

BACKGROUND: Complex diseases may have multiple pathways leading to disease. E.g. coronary artery disease evolves from arterial damage to their epithelial layers, but has multiple causal pathways. More challenging, those pathways are highly correlated within metabolic syndrome. The challenge is to id...

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Detalles Bibliográficos
Autores principales: Platt, Daniel E., Basu, Saugata, Zalloua, Pierre A., Parida, Laxmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895260/
https://www.ncbi.nlm.nih.gov/pubmed/26819062
http://dx.doi.org/10.1186/s12918-015-0251-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895260/
https://www.ncbi.nlm.nih.gov/pubmed/26819062
http://dx.doi.org/10.1186/s12918-015-0251-2

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