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Characterizing redescriptions using persistent homology to isolate genetic pathways contributing to pathogenesis
BACKGROUND: Complex diseases may have multiple pathways leading to disease. E.g. coronary artery disease evolves from arterial damage to their epithelial layers, but has multiple causal pathways. More challenging, those pathways are highly correlated within metabolic syndrome. The challenge is to id...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895260/ https://www.ncbi.nlm.nih.gov/pubmed/26819062 http://dx.doi.org/10.1186/s12918-015-0251-2 |