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NMFP: a non-negative matrix factorization based preselection method to increase accuracy of identifying mRNA isoforms from RNA-seq data

BACKGROUND: The advent of next-generation RNA sequencing (RNA-seq) has greatly advanced transcriptomic studies, including system-wide identification and quantification of mRNA isoforms under various biological conditions. A number of computational methods have been developed to systematically identi...

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Detalles Bibliográficos
Autores principales: Ye, Yuting, Li, Jingyi Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895266/
https://www.ncbi.nlm.nih.gov/pubmed/26818007
http://dx.doi.org/10.1186/s12864-015-2304-8