A Bayesian approach for estimating allele-specific expression from RNA-Seq data with diploid genomes

BACKGROUND: RNA-sequencing (RNA-Seq) has become a popular tool for transcriptome profiling in mammals. However, accurate estimation of allele-specific expression (ASE) based on alignments of reads to the reference genome is challenging, because it contains only one allele on a mosaic haploid genome....

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Detalles Bibliográficos
Autores principales: Nariai, Naoki, Kojima, Kaname, Mimori, Takahiro, Kawai, Yosuke, Nagasaki, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895278/
https://www.ncbi.nlm.nih.gov/pubmed/26818838
http://dx.doi.org/10.1186/s12864-015-2295-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895278/
https://www.ncbi.nlm.nih.gov/pubmed/26818838
http://dx.doi.org/10.1186/s12864-015-2295-5

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