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A Bayesian approach for estimating allele-specific expression from RNA-Seq data with diploid genomes
BACKGROUND: RNA-sequencing (RNA-Seq) has become a popular tool for transcriptome profiling in mammals. However, accurate estimation of allele-specific expression (ASE) based on alignments of reads to the reference genome is challenging, because it contains only one allele on a mosaic haploid genome....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895278/ https://www.ncbi.nlm.nih.gov/pubmed/26818838 http://dx.doi.org/10.1186/s12864-015-2295-5 |