Prediction of drugs having opposite effects on disease genes in a directed network

BACKGROUND: Developing novel uses of approved drugs, called drug repositioning, can reduce costs and times in traditional drug development. Network-based approaches have presented promising results in this field. However, even though various types of interactions such as activation or inhibition exi...

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Detalles Bibliográficos
Autores principales: Yu, Hasun, Choo, Sungji, Park, Junseok, Jung, Jinmyung, Kang, Yeeok, Lee, Doheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895308/
https://www.ncbi.nlm.nih.gov/pubmed/26818006
http://dx.doi.org/10.1186/s12918-015-0243-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895308/
https://www.ncbi.nlm.nih.gov/pubmed/26818006
http://dx.doi.org/10.1186/s12918-015-0243-2

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