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Prediction of drugs having opposite effects on disease genes in a directed network
BACKGROUND: Developing novel uses of approved drugs, called drug repositioning, can reduce costs and times in traditional drug development. Network-based approaches have presented promising results in this field. However, even though various types of interactions such as activation or inhibition exi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895308/ https://www.ncbi.nlm.nih.gov/pubmed/26818006 http://dx.doi.org/10.1186/s12918-015-0243-2 |