Cargando…

Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway

Mutation of PPP2R1A has been observed at high frequency in endometrial serous carcinomas but at low frequency in ovarian clear cell carcinoma. However, the biological role of mutation of PPP2R1A in ovarian and endometrial cancer progression remains unclear. In this study, we found that PPP2R1A expre...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, Ae Lee, Han, Sora, Lee, Sunyi, Su Park, Jeong, Lu, Yiling, Yu, Shuangxing, Li, Jane, Chun, Kyung-Hee, Mills, Gordon B., Yang, Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895347/
https://www.ncbi.nlm.nih.gov/pubmed/27272709
http://dx.doi.org/10.1038/srep27391