Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells

The proliferation and survival of hematopoietic stem cells (HSCs) has to be strictly coordinated to ensure the timely production of all blood cells. Here we report that the splice factor and RNA binding protein hnRNP L (heterogeneous nuclear ribonucleoprotein L) is required for hematopoiesis, since...

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Detalles Bibliográficos
Autores principales: Gaudreau, Marie-Claude, Grapton, Damien, Helness, Anne, Vadnais, Charles, Fraszczak, Jennifer, Shooshtarizadeh, Peiman, Wilhelm, Brian, Robert, François, Heyd, Florian, Möröy, Tarik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895350/
https://www.ncbi.nlm.nih.gov/pubmed/27271479
http://dx.doi.org/10.1038/srep27379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895350/
https://www.ncbi.nlm.nih.gov/pubmed/27271479
http://dx.doi.org/10.1038/srep27379

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