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Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice

Several genome- and proteome-wide studies have associated transcription and translation changes of CRMP2 (collapsing response mediator protein 2) with psychiatric disorders, yet little is known about its function in the developing or adult mammalian brain in vivo. Here we show that brain-specific Cr...

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Detalles Bibliográficos
Autores principales: Zhang, Hongsheng, Kang, Eunchai, Wang, Yaqing, Yang, Chaojuan, Yu, Hui, Wang, Qin, Chen, Zheyu, Zhang, Chen, Christian, Kimberly M., Song, Hongjun, Ming, Guo-li, Xu, Zhiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895353/
https://www.ncbi.nlm.nih.gov/pubmed/27249678
http://dx.doi.org/10.1038/ncomms11773