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Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity
BACKGROUND/OBJECTIVES: The uroguanylin-GUCY2C gut–brain axis has emerged as one component regulating feeding, energy homeostasis, body mass and metabolism. Here, we explore a role for this axis in mechanisms underlying diet-induced obesity (DIO). SUBJECTS/METHODS: Intestinal uroguanylin expression a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895379/ https://www.ncbi.nlm.nih.gov/pubmed/27214655 http://dx.doi.org/10.1038/nutd.2016.18 |