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Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity

BACKGROUND/OBJECTIVES: The uroguanylin-GUCY2C gut–brain axis has emerged as one component regulating feeding, energy homeostasis, body mass and metabolism. Here, we explore a role for this axis in mechanisms underlying diet-induced obesity (DIO). SUBJECTS/METHODS: Intestinal uroguanylin expression a...

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Detalles Bibliográficos
Autores principales:	Kim, G W, Lin, J E, Snook, A E, Aing, A S, Merlino, D J, Li, P, Waldman, S A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895379/ https://www.ncbi.nlm.nih.gov/pubmed/27214655 http://dx.doi.org/10.1038/nutd.2016.18

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