The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling

Tumour necrosis factor receptor-associated factor 6 (TRAF6) is a ubiquitin E3 ligase that regulates important biological processes. However, the role of TRAF6 in cardiac hypertrophy remains unknown. Here, we show that TRAF6 levels are increased in human and murine hypertrophied hearts, which is regu...

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Detalles Bibliográficos
Autores principales: Ji, Yan-Xiao, Zhang, Peng, Zhang, Xiao-Jing, Zhao, Yi-Chao, Deng, Ke-Qiong, Jiang, Xi, Wang, Pi-Xiao, Huang, Zan, Li, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895385/
https://www.ncbi.nlm.nih.gov/pubmed/27249171
http://dx.doi.org/10.1038/ncomms11267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895385/
https://www.ncbi.nlm.nih.gov/pubmed/27249171
http://dx.doi.org/10.1038/ncomms11267

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