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Convulsive seizures from experimental focal cortical dysplasia occur independently of cell misplacement

Focal cortical dysplasia (FCD), a local malformation of cortical development, is the most common cause of pharmacoresistant epilepsy associated with life-long neurocognitive impairments. It remains unclear whether neuronal misplacement is required for seizure activity. Here we show that dyslaminatio...

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Detalles Bibliográficos
Autores principales: Hsieh, Lawrence S., Wen, John H., Claycomb, Kumiko, Huang, Yuegao, Harrsch, Felicia A., Naegele, Janice R., Hyder, Fahmeed, Buchanan, Gordon F., Bordey, Angelique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895394/
https://www.ncbi.nlm.nih.gov/pubmed/27249187
http://dx.doi.org/10.1038/ncomms11753