Identification of PDE5A:E90K: A Polymorphism in the Canine Phosphodiesterase 5A Gene Affecting Basal cGMP Concentrations of Healthy Dogs

BACKGROUND: Cyclic guanosine monophosphate (cGMP)‐specific phosphodiesterase (PDE5A) is the target of phosphodiesterase inhibitors such as sildenafil. Polymorphisms in the PDE5A gene that may predict response to therapy with sildenafil and nitric oxide, be linked to disease progression, and aid in r...

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Detalles Bibliográficos
Autores principales: Stern, J. A., Reina‐Doreste, Y., Chdid, L., Meurs, K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Standard Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895552/
https://www.ncbi.nlm.nih.gov/pubmed/24341639
http://dx.doi.org/10.1111/jvim.12256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895552/
https://www.ncbi.nlm.nih.gov/pubmed/24341639
http://dx.doi.org/10.1111/jvim.12256

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