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Serotonin Concentrations in Platelets, Plasma, Mitral Valve Leaflet, and Left Ventricular Myocardial Tissue in Dogs with Myxomatous Mitral Valve Disease

HYPOTHESIS/OBJECTIVES: Altered serotonin (5‐hydroxytryptamine, 5HT) signaling is postulated in development and progression of canine myxomatous mitral valve disease (MMVD). Little is known regarding platelet, plasma, valvular, or myocardial 5HT concentration ([5HT]) in affected dogs. We quantified [...

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Detalles Bibliográficos
Autores principales: Cremer, S.E., Singletary, G.E., Olsen, L.H., Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C.A., Pizzinat, N., Oyama, M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895588/
https://www.ncbi.nlm.nih.gov/pubmed/25146933
http://dx.doi.org/10.1111/jvim.12420