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Frequent variations in cancer-related genes may play prognostic role in treatment of patients with chronic myeloid leukemia

BACKGROUND: Genome variability of host genome and cancer cells play critical role in diversity of response to existing therapies and overall success in treating oncological diseases. In chronic myeloid leukemia targeted therapy with tyrosine kinase inhibitors demonstrates high efficacy in most of th...

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Detalles Bibliográficos
Autores principales: Lavrov, Alexander V., Chelysheva, Ekaterina Y., Smirnikhina, Svetlana A., Shukhov, Oleg A., Turkina, Anna G., Adilgereeva, Elmira P., Kutsev, Sergey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895599/
https://www.ncbi.nlm.nih.gov/pubmed/26822197
http://dx.doi.org/10.1186/s12863-015-0308-7