Filtering genetic variants and placing informative priors based on putative biological function

High-density genetic marker data, especially sequence data, imply an immense multiple testing burden. This can be ameliorated by filtering genetic variants, exploiting or accounting for correlations between variants, jointly testing variants, and by incorporating informative priors. Priors can be ba...

Descripción completa

Detalles Bibliográficos
Autores principales: Friedrichs, Stefanie, Malzahn, Dörthe, Pugh, Elizabeth W., Almeida, Marcio, Liu, Xiao Qing, Bailey, Julia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895695/
https://www.ncbi.nlm.nih.gov/pubmed/26866982
http://dx.doi.org/10.1186/s12863-015-0313-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895695/
https://www.ncbi.nlm.nih.gov/pubmed/26866982
http://dx.doi.org/10.1186/s12863-015-0313-x

Ejemplares similares