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The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes

BACKGROUND: Thyroid carcinomas are known to harbor oncogenic driver mutations and advances in sequencing technology now allow the detection of these in fine needle aspiration biopsies (FNA). Recent work by The Cancer Genome Atlas (TCGA) Research Network has expanded the number of genetic alterations...

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Detalles Bibliográficos
Autores principales: Pagan, Moraima, Kloos, Richard T., Lin, Chu-Fang, Travers, Kevin J., Matsuzaki, Hajime, Tom, Ed Y., Kim, Su Yeon, Wong, Mei G., Stewart, Andrew C., Huang, Jing, Walsh, P. Sean, Monroe, Robert J., Kennedy, Giulia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895782/
https://www.ncbi.nlm.nih.gov/pubmed/26818556
http://dx.doi.org/10.1186/s12859-015-0849-9