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Platelets activation is associated with elevated plasma mitochondrial DNA during cardiopulmonary bypass

BACKGROUND: Mitochondrial DNA (mtDNA) was reported as a pro-inflammatory agent. In our previous study, elevation of plasma mtDNA was revealed after cardiac surgery with cardiopulmonary bypass (CPB). Platelets were activated during the cardiac surgery and recent study revealed its ability to release...

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Detalles Bibliográficos
Autores principales: Qin, Chaoyi, Gu, Jun, Hu, Jia, Qian, Hong, Fei, Xu, Li, Yajiao, Liu, Ruiqi, Meng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895797/
https://www.ncbi.nlm.nih.gov/pubmed/27266529
http://dx.doi.org/10.1186/s13019-016-0481-4