Rebalancing gene haploinsufficiency in vivo by targeting chromatin

Congenital heart disease (CHD) affects eight out of 1,000 live births and is a major social and health-care burden. A common genetic cause of CHD is the 22q11.2 deletion, which is the basis of the homonymous deletion syndrome (22q11.2DS), also known as DiGeorge syndrome. Most of its clinical spectru...

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Detalles Bibliográficos
Autores principales: Fulcoli, Filomena Gabriella, Franzese, Monica, Liu, Xiangyang, Zhang, Zhen, Angelini, Claudia, Baldini, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895808/
https://www.ncbi.nlm.nih.gov/pubmed/27256596
http://dx.doi.org/10.1038/ncomms11688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895808/
https://www.ncbi.nlm.nih.gov/pubmed/27256596
http://dx.doi.org/10.1038/ncomms11688

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