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Design of trials for interrupting the transmission of endemic pathogens

BACKGROUND: Many interventions against infectious diseases have geographically diffuse effects. This leads to contamination between arms in cluster-randomized trials (CRTs). Pathogen elimination is the goal of many intervention programs against infectious agents, but contamination means that standar...

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Detalles Bibliográficos
Autores principales: Silkey, Mariabeth, Homan, Tobias, Maire, Nicolas, Hiscox, Alexandra, Mukabana, Richard, Takken, Willem, Smith, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895826/
https://www.ncbi.nlm.nih.gov/pubmed/27266269
http://dx.doi.org/10.1186/s13063-016-1378-1