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Altered Secretory Activity of APE1/Ref-1 D148E Variants Identified in Human Patients With Bladder Cancer

PURPOSE: Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is a multifunctional protein involved in DNA repair and redox modulation. Recently, serum and urinary APE1/Ref-1 levels were reported to be increased in patients with bladder cancer. Genetic variations of APE/Ref-1 are associa...

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Detalles Bibliográficos
Autores principales: Lee, Yu Ran, Lim, Jae Sung, Shin, Ju Hyun, Choi, Sunga, Joo, Hee Kyoung, Jeon, Byeong Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Continence Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895906/
https://www.ncbi.nlm.nih.gov/pubmed/27230458
http://dx.doi.org/10.5213/inj.1632600.300