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Transcriptome analysis of human brain tissue identifies reduced expression of complement complex C1Q Genes in Rett syndrome

BACKGROUND: MECP2, the gene mutated in the majority of Rett syndrome cases, is a transcriptional regulator that can activate or repress transcription. Although the transcription regulatory function of MECP2 has been known for over a decade, it remains unclear how transcriptional dysregulation leads...

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Detalles Bibliográficos
Autores principales: Lin, Peijie, Nicholls, Laura, Assareh, Hassan, Fang, Zhiming, Amos, Timothy G., Edwards, Richard J., Assareh, Amelia A., Voineagu, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895974/
https://www.ncbi.nlm.nih.gov/pubmed/27267200
http://dx.doi.org/10.1186/s12864-016-2746-7