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Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself

BACKGROUND: Interleukin (IL)-1β is a pro-inflammatory cytokine that plays a role in the pathogenesis of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), the animal model for MS. Yet, detailed studies on IL-1β expression in different stages of MS lesion development and a c...

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Detalles Bibliográficos
Autores principales: Burm, Saskia Maria, Peferoen, Laura Anna Norma, Zuiderwijk-Sick, Ella Alwine, Haanstra, Krista Geraldine, ‘t Hart, Bert Adriaan, van der Valk, Paul, Amor, Sandra, Bauer, Jan, Bajramovic, Jeffrey John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895983/
https://www.ncbi.nlm.nih.gov/pubmed/27266875
http://dx.doi.org/10.1186/s12974-016-0605-8