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Serum 8-hydroxy-2-deoxyguanosine as a marker of DNA oxidative damage in horses with recurrent airway obstruction

BACKGROUND: It has been reported that equine recurrent airway obstruction (RAO) is a state of oxidative stress. Oxidant-antioxidant imbalance is known to increase the conversion of deoxyguanosine to 8-hydroxy-2-deoxyguanosine (8-OHdG) in DNA. 8-OHdG can easily be measured using ELISA tests in serum...

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Detalles Bibliográficos
Autores principales: Niedzwiedz, Artur, Borowicz, Hieronim, Januszewska, Lidia, Markiewicz-Gorka, Iwona, Jaworski, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895991/
https://www.ncbi.nlm.nih.gov/pubmed/27267076
http://dx.doi.org/10.1186/s13028-016-0215-6