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BluePyOpt: Leveraging Open Source Software and Cloud Infrastructure to Optimise Model Parameters in Neuroscience

At many scales in neuroscience, appropriate mathematical models take the form of complex dynamical systems. Parameterizing such models to conform to the multitude of available experimental constraints is a global non-linear optimisation problem with a complex fitness landscape, requiring numerical t...

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Detalles Bibliográficos
Autores principales: Van Geit, Werner, Gevaert, Michael, Chindemi, Giuseppe, Rössert, Christian, Courcol, Jean-Denis, Muller, Eilif B., Schürmann, Felix, Segev, Idan, Markram, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896051/
https://www.ncbi.nlm.nih.gov/pubmed/27375471
http://dx.doi.org/10.3389/fninf.2016.00017