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Concentrating pre-mRNA processing factors in the histone locus body facilitates efficient histone mRNA biogenesis

The histone locus body (HLB) assembles at replication-dependent histone genes and concentrates factors required for histone messenger RNA (mRNA) biosynthesis. FLASH (Flice-associated huge protein) and U7 small nuclear RNP (snRNP) are HLB components that participate in 3′ processing of the nonpolyade...

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Detalles Bibliográficos
Autores principales: Tatomer, Deirdre C., Terzo, Esteban, Curry, Kaitlin P., Salzler, Harmony, Sabath, Ivan, Zapotoczny, Grzegorz, McKay, Daniel J., Dominski, Zbigniew, Marzluff, William F., Duronio, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896052/
https://www.ncbi.nlm.nih.gov/pubmed/27241916
http://dx.doi.org/10.1083/jcb.201504043