Num1 anchors mitochondria to the plasma membrane via two domains with different lipid binding specificities

The mitochondria–ER cortex anchor (MECA) is required for proper mitochondrial distribution and functions by tethering mitochondria to the plasma membrane. The core component of MECA is the multidomain protein Num1, which assembles into clusters at the cell cortex. We show Num1 adopts an extended, po...

Descripción completa

Detalles Bibliográficos
Autores principales: Ping, Holly A., Kraft, Lauren M., Chen, WeiTing, Nilles, Amy E., Lackner, Laura L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896055/
https://www.ncbi.nlm.nih.gov/pubmed/27241910
http://dx.doi.org/10.1083/jcb.201511021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896055/
https://www.ncbi.nlm.nih.gov/pubmed/27241910
http://dx.doi.org/10.1083/jcb.201511021

Ejemplares similares