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T cell activation requires force generation

Triggering of the T cell receptor (TCR) integrates both binding kinetics and mechanical forces. To understand the contribution of the T cell cytoskeleton to these forces, we triggered T cells using a novel application of atomic force microscopy (AFM). We presented antigenic stimulation using the AFM...

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Detalles Bibliográficos
Autores principales: Hu, Kenneth H., Butte, Manish J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896056/
https://www.ncbi.nlm.nih.gov/pubmed/27241914
http://dx.doi.org/10.1083/jcb.201511053