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MICOS and phospholipid transfer by Ups2–Mdm35 organize membrane lipid synthesis in mitochondria

Mitochondria exert critical functions in cellular lipid metabolism and promote the synthesis of major constituents of cellular membranes, such as phosphatidylethanolamine (PE) and phosphatidylcholine. Here, we demonstrate that the phosphatidylserine decarboxylase Psd1, located in the inner mitochond...

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Detalles Bibliográficos
Autores principales: Aaltonen, Mari J., Friedman, Jonathan R., Osman, Christof, Salin, Bénédicte, di Rago, Jean-Paul, Nunnari, Jodi, Langer, Thomas, Tatsuta, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896057/
https://www.ncbi.nlm.nih.gov/pubmed/27241913
http://dx.doi.org/10.1083/jcb.201602007