Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury

Aims: Myocardial ischemia can result in marked mitochondrial damage leading to cardiac dysfunction, as such identifying novel mechanisms to limit mitochondrial injury is important. This study investigated the hypothesis that inhibiting soluble epoxide hydrolase (sEH), responsible for converting epox...

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Detalles Bibliográficos
Autores principales: Akhnokh, Maria K., Yang, Feng Hua, Samokhvalov, Victor, Jamieson, Kristi L., Cho, Woo Jung, Wagg, Cory, Takawale, Abhijit, Wang, Xiuhua, Lopaschuk, Gary D., Hammock, Bruce D., Kassiri, Zamaneh, Seubert, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896112/
https://www.ncbi.nlm.nih.gov/pubmed/27375480
http://dx.doi.org/10.3389/fphar.2016.00133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896112/
https://www.ncbi.nlm.nih.gov/pubmed/27375480
http://dx.doi.org/10.3389/fphar.2016.00133

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