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A novel molecular dynamics approach to evaluate the effect of phosphorylation on multimeric protein interface: the αB-Crystallin case study

BACKGROUND: Phosphorylation is one of the most important post-translational modifications (PTM) employed by cells to regulate several cellular processes. Studying the effects of phosphorylations on protein structures allows to investigate the modulation mechanisms of several proteins including chape...

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Detalles Bibliográficos
Autores principales: Chiappori, Federica, Mattiazzi, Luca, Milanesi, Luciano, Merelli, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896236/
https://www.ncbi.nlm.nih.gov/pubmed/26961246
http://dx.doi.org/10.1186/s12859-016-0909-9