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A novel molecular dynamics approach to evaluate the effect of phosphorylation on multimeric protein interface: the αB-Crystallin case study
BACKGROUND: Phosphorylation is one of the most important post-translational modifications (PTM) employed by cells to regulate several cellular processes. Studying the effects of phosphorylations on protein structures allows to investigate the modulation mechanisms of several proteins including chape...
Autores principales: | Chiappori, Federica, Mattiazzi, Luca, Milanesi, Luciano, Merelli, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896236/ https://www.ncbi.nlm.nih.gov/pubmed/26961246 http://dx.doi.org/10.1186/s12859-016-0909-9 |
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