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The absence of dysferlin induces the expression of functional connexin-based hemichannels in human myotubes
BACKGROUND: Mutations in the gene encoding for dysferlin cause recessive autosomal muscular dystrophies called dysferlinopathies. These mutations induce several alterations in skeletal muscles, including, inflammation, increased membrane permeability and cell death. Despite the fact that the etiolog...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896263/ https://www.ncbi.nlm.nih.gov/pubmed/27229680 http://dx.doi.org/10.1186/s12860-016-0096-6 |