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Fast, accurate, and lightweight analysis of BS-treated reads with ERNE 2

BACKGROUND: Bisulfite treatment of DNA followed by sequencing (BS-seq) has become a standard technique in epigenetic studies, providing researchers with tools for generating single-base resolution maps of whole methylomes. Aligning bisulfite-treated reads, however, is a computationally difficult tas...

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Detalles Bibliográficos
Autores principales: Prezza, Nicola, Vezzi, Francesco, Käller, Max, Policriti, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896272/
https://www.ncbi.nlm.nih.gov/pubmed/26961371
http://dx.doi.org/10.1186/s12859-016-0910-3