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Fast, accurate, and lightweight analysis of BS-treated reads with ERNE 2
BACKGROUND: Bisulfite treatment of DNA followed by sequencing (BS-seq) has become a standard technique in epigenetic studies, providing researchers with tools for generating single-base resolution maps of whole methylomes. Aligning bisulfite-treated reads, however, is a computationally difficult tas...
Autores principales: | Prezza, Nicola, Vezzi, Francesco, Käller, Max, Policriti, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896272/ https://www.ncbi.nlm.nih.gov/pubmed/26961371 http://dx.doi.org/10.1186/s12859-016-0910-3 |
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