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CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array

The Illumina Infinium HumanMethylation450 BeadChip (450k) is widely used for the evaluation of DNA methylation levels in large-scale datasets, particularly in cancer. The 450k design allows copy number variant (CNV) calling using existing bioinformatics tools. However, in cancer samples, numerous la...

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Detalles Bibliográficos
Autores principales: Marzouka, Nour-al-dain, Nordlund, Jessica, Bäcklin, Christofer L., Lönnerholm, Gudmar, Syvänen, Ann-Christine, Carlsson Almlöf, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896365/
https://www.ncbi.nlm.nih.gov/pubmed/26553913
http://dx.doi.org/10.1093/bioinformatics/btv652