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The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells

The transcription factor Glis-similar 3 (Glis3) has been implicated in the development of neonatal, type 1 and type 2 diabetes. In this study, we examined the spatiotemporal expression of Glis3 protein during embryonic and neonatal pancreas development as well as its function in PP cells. To obtain...

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Detalles Bibliográficos
Autores principales: Kang, Hong Soon, Takeda, Yukimasa, Jeon, Kilsoo, Jetten, Anton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896454/
https://www.ncbi.nlm.nih.gov/pubmed/27270601
http://dx.doi.org/10.1371/journal.pone.0157138